Grapefruit and Prescription Medications

by on March 11, 2012

Fruit is an essential part of a healthy diet. While it is recommended to eat a few servings of fruit each day, it is also important to note that certain fruits can interfere with the pharmacological action of certain medications. Some of these interactions may have minor side effects, but unfortunately, others may cause side effects, which can be life threatening, or even fatal.

The FDA has recently issued a reminder that Grapefruit is one fruit that has the ability to interact with many prescription medications and according to a study one in five Americans eat or drink Grapefruit every day for breakfast.

Grapefruit May Increase or Decrease Drug Potency

Prescription Drugs and Grapefruit JuiceDepending on the type of medication, grapefruit has the ability to either weaken or strengthen its pharmacological action. In other words, it can either result in the drug not working at all or it can cause the drug to be too potent, which can lead to devastating side effects either way.

With some medications, the active compound in grapefruit juice (bergamottin) prevents the enzymes in the small intestine from doing their job, leading to a higher dose of the medication being absorbed by the body. This can lead to an overdose, which can be fatal.

Other medications are moved into the body’s cells by means of transporter proteins. Grapefruit has the ability to prevent these transporters from doing their job, which can then reduce the effectiveness of the medication.

Today, many pharmaceutical manufacturers state that their medications should not be taken with fruit juice. Because of these interactions, the FDA requires certain prescription medications to carry a warning about consuming grapefruit or grapefruit juice during use.  It is important to note that these warnings also apply to certain non-prescription medications. That is why it is always recommended that the patient read the package insert that comes with the medication. If no mention is made about grapefruit or grapefruit juice, it is always best to consult with a doctor before consuming it during your treatment.   Patients also need to ensure that other foods and juices they consume do not contain grapefruit or grapefruit juice while using certain medications.How_Grapefruit_Juice_Affects_Some_Medications

Grapefruit Affects a Variety of Pharmaceuticals

Many pharmaceuticals are affected by grapefruit or grapefruit juice. Even consuming it a few hours before or after taking the drug can affect the absorption rate of many medications. Types of pharmaceuticals that are affected include:

Because it is impossible to list every single pharmaceutical here which may be affected by grapefruit or grapefruit juice, it is important to consult with your doctor if you are unsure about any possible side-effects or interactions.  For a more complete list you can visit this Wikipedia entry:  http://en.wikipedia.org/wiki/Grapefruit_drug_interactions

Should You Stop Grapefruit Use?

grapefruit and medicationsIf any of the drugs or medications you take are mentioned above then you should talk with your doctor to receive his or hers advice.   If your medication is known to interact adversely with Grapefuit, then your doctor may present you with other options.  In most cases, though it might be best to cut back on your consumption of grapefruit and grapefruit juice during the course of your treatment.

If your medication is not known to adversely interact with grapefruit and grapefruit juice then there’s no reason to stop its consumption, especially since grapefruit is an excellent source fo Vitamin C and can have a positive impact on your heart health.

Share this page


Add A Comment

5 Responses

Required fields are marked *

  1. Shirley Skove

    I would like to know side effects on drug Jalyn

  2. Andrea

    Grapes is good for the heart.But how much calorie does grapes had?

  3. Ha-ha excellent old days of e-books, AdWords, and AdSense when you might plaster your DUY web site with banners, kick back and collect the cash:-RRB- ...
    Affiliate marketing is probably the best option for newbie blog writers, especially Amazon (as long as you know how to
    do it, and NOT greedy/sketchy ). But yeah, totally free sponsored trips and free gear (SWAG -shit we all get:
    -RRB-)were the first things I was getting when I began.

  4. I have fun with, lead to I found just what I used to be looking for.
    You've ended my 4 day lengthy hunt! God Bless you man. Have a great day.
    Bye

  5. You'll need to do a great deal of hoping and image repair work to obtain your sweetheart to even think about trusting you again.

« | »