Oxybutynin Drug Interactions

by on April 16, 2012

Some medications interfere with the efficacy of Oxybutynin and vice-versa; others can worsen side effects. If you are taking any of these medications, discuss them with your physician prior to accepting a prescription for Oxybutynin.

  • Other anticholinergic or anti-spasmodic medications (Atovent, Diphenhydramine, Spiriva, Detrol, Dramamine, etc.)
  • Some Parkinson’s disease medications (such as benztropine and trihexyphenidyl)
  • Belladonna alkaloids
  • Biphosphonates (alendronate, etidronate, etc.)
  • Azole antifungal drugs (ketoconazole, macrolide)
  • Some anti-anxiety medications like Valium (diazepam)
  • Anti-seizure medications (phenobarbital, carbamazepine)
  • Sleep-inducing medications (Ambien - zolpidem)
  • Some antibiotics (erythromycin, cimetidine)
  • St. John’s Wort
  • Potassium supplements
  • Codeine
  • Antidepressants and anti-psychotic medication (tricyclic antidepressants, amitriptyline, chlorpromazine)

Always discuss any natural remedies, vitamin/mineral supplements, over-the-counter medications, and prescription drugs you may be taking prior to accepting a prescription for Ditropan.