Reglan (metoclopramide) is classified as a “prokinetic” drug that works on the gastrointestinal tract. It stimulates muscular activity of the small intestine, stomach and lower esophageal sphincter thereby increasing clearance of gastrointestinal contents.
Raglan is most commonly used to relieve symptoms of heartburn related with gastroesophageal reflux disease (GERD), especially if other treatments fail. It may also be used to relieve heartburn after meals and daytime heartburn. For patients with ulcer in the esophagus, Reglan is prescribed to aid in the immediate healing of the ulcer. For diabetics, this drug can relieve symptoms of slow stomach clearance such as loss of appetite, nausea, vomiting, feeling of fullness hours after a meal, and heartburn.
Furthermore, Reglan is used to manage the adverse effects of cancer chemotherapy particularly nausea and vomiting. It is also taken by patients before X-ray examination of the gastrointestinal tract. It may also be prescribed to patients undergoing medical and surgical procedures that involve manipulation of the small intestine.
What is the usual Reglan dosage?
Reglan dosage depends on your medical condition and health history. Below is general information about Reglan dosage. Your healthcare provider may prescribe a completely different regimen depending on your unique needs.
Like in any other medications, do not adjust or discontinue Reglan without recommendation of your physician.
Symptomatic Relief of GERD
For adults, the usual oral dose of Reglan for relief of GERD symptoms is 10 mg to 15 mg. The frequency and duration of treatment depends on the severity of the symptoms and the patient’s response to the treatment. Usually, it is given 3 to 4 times a day, 30 minutes before meals and/or before sleeping for 12 weeks. For patients whose symptoms occur intermittently, the physician may recommend single dose of Reglan up to 20 mg only to prevent the symptom.
The geriatric dose of Reglan is usually 5 mg per dose and may be adjusted accordingly.
Symptomatic Relief of Diabetic Slow Stomach Emptying (Diabetic Gastroparesis)
For adults, the usual oral dose of Reglan for relief of symptoms of diabetic slow stomach emptying is 10 mg taken 30 minutes before meals and before sleeping for 2 to 8 weeks. However, patients suffering from severe symptoms may be given initial doses of Reglan Injection (IM or IV) through intravenous route until the patient can tolerate the oral route.
Other Medical Conditions
For prevention of nausea and vomiting in patients undergoing chemotherapy, Reglan Injection is administered slowly as intravenous infusion prior, during and after the cancer chemotherapy. Doses are adjusted according to the needs of the clients, the chemotherapy drug used and the client’s previous response to chemotherapy.
For prevention of nausea and vomiting post-surgery, Reglan Injection is administered near the end of the procedure. Usual dose is 10 mg but may be adjusted to 20 mg.
To facilitate bowel intubation and aid in radiologic examination, single dose of 10 mg Reglan Injection may be given slowly through the intravenous route.
Patients with hepatic or renal impairment may be given half dose and require close medical supervision to avoid drug toxicity.