Colchicine During Pregnancy & Breastfeeding

Colchicine (Colcrys) has been assigned by the FDA as a category C drug in regards to pregnancy. Animal studies have revealed evidence of teratogenicity, but there are no controlled data experiments for human pregnancy.

It is suspected that colchicine crosses the human placenta, but no evidence has been found that the drug carries an increased risk of still birth or miscarriage. However, this medication should only be used during pregnancy when there are no other options.

Colchicine is also excreted into human milk, but there are no published reports of adverse effects in breast-fed babies.