Nexium and Alcohol

by on May 16, 2012

When Nexium and alcohol are taken in combination, there are generally no adverse effects. However, as each patient is different and may be more affected by certain drug combinations than others, it is advisable for people taking Nexium to consult a healthcare provider before drinking alcohol.

Potential Side Effects

Although there is usually no problem with drinking while on Nexium (Esomeprazole), be aware that alcohol can increase acid reflux, thus defeating the purpose of Nexium, which is an anti-heartburn medication.

In some cases, alcohol may interact with Nexium by increasing the risk and severity of the medication’s side effects. Side effects associated with Nexium include dry mouth, constipation, diarrhea, breathing problems, swelling, unusual bleeding and chest pain. Therefore, if the patient is already vulnerable to any of these conditions or symptoms, he or she should proceed with caution when combining alcohol with this drug.

To tell if a patient is suffering adverse effects from combining Nexium and alcohol, there are several signs and symptoms to look out for. He or she may be experiencing severe allergic reactions that physically manifest themselves as a rash, hives, unusual hoarseness or swelling of the mouth, face, lips, or tongue. Their urine may be dark and their eyes or skin might appear to be jaundiced. If the patient is exhibiting any of these symptoms to a severe extent, seek medical assistance as soon as possible.


If a patient is particularly at risk of these side effects, it is advised that alcohol be consumed in moderation while taking Nexium.

The medical community generally defines moderate alcohol consumption as no more than 2 units per day and no more than 14 units per week. To manage alcohol intake responsibly, try keeping a written record of alcoholic drinks consumed and drinking a glass of water after each drink. If necessary, it can also be helpful to consult a healthcare provider on controlling alcohol consumption.

Although expert advice suggests alcohol consumption is okay while taking Nexium, it’s important to remain alert to the possibilities of the combination having an adverse effect. If any unusual symptoms or side effects occur after combining Nexium with alcohol, consult a healthcare provider.