Oxybutynin Drug Interactions

Some medications interfere with the efficacy of Oxybutynin and vice-versa; others can worsen side effects. If you are taking any of these medications, discuss them with your physician prior to accepting a prescription for Oxybutynin.

• Other anticholinergic or anti-spasmodic medications (Atovent, Diphenhydramine, Spiriva, Detrol, Dramamine, etc.)
• Some Parkinson’s disease medications (such as benztropine and trihexyphenidyl)
• Belladonna alkaloids
• Biphosphonates (alendronate, etidronate, etc.)
• Azole antifungal drugs (ketoconazole, macrolide)
• Some anti-anxiety medications like Valium (diazepam)
• Anti-seizure medications (phenobarbital, carbamazepine)
• Sleep-inducing medications (Ambien - zolpidem)
• Some antibiotics (erythromycin, cimetidine)
• St. John’s Wort
• Potassium supplements
• Codeine
• Antidepressants and anti-psychotic medication (tricyclic antidepressants, amitriptyline, chlorpromazine)

Always discuss any natural remedies, vitamin/mineral supplements, over-the-counter medications, and prescription drugs you may be taking prior to accepting a prescription for Ditropan.