Lantus Drug Interactions

by on April 18, 2012

The use of other drugs and medications can have an effect on the effectiveness of Lantus. Certain drugs can make it more difficult for patients to determine when they have low blood sugar.

Insulin glargine (Lantus®) potentially can interact with a number of additional medications; however, there will be too many to list in this guide.   So be sure to consult with your doctor before starting any new medications while on Lantus.

Here's are a few drugs which may adversely interact with Lantus:

  •  ACE (Angiotensin-converting enzyme) inhibitors, like:
    • Ramipril (Altace®)
    • Quinapril (Accuretic® and Accupril®)
    • Lisinopril (Zestoretic®, Zestril®, Prinzide®, and Prinivil®)
    • Fosinopril (Monopril® and Monopril-HCT®)
    • Enalapril (Lexxel®, Vaseretic®, and Vasotec®)
    • Captopril (Capozide® and Capoten®)
    • Benazepril (Lotrel®, Lotensin®HCT, and Lotensin®)
  • Beta blockers, like:
    • Labetalol (Trandate®)
    • Carvedilol (Coreg®)
    • Timolol (Blocadren)
    • Sotalol (Betapace®)
    • Propranolol (Inderal®)
    • Nadolol (Corgard®)
    • Metoprolol (Toprol XL®, and Lopressor®)
    • Bisoprolol (Zebeta®)
    • Atenolol (Tenormin®)
  •  Disopyramide (Norpace® CR, and Norpace®) Fibrates, like:
    • Gemfibrozil (Lopid®)
    • Fenofibrate (Triglide™, Tricor®, Lofibra™, and Antara™)
  • MAOIs (Monoamine oxidase inhibitors), like:
    • Reserpine
    • Propoxyphene (Darvocet®, and Darvon®)
    • Oral diabetes medicines
    • Octreotide (Sandostatin®)
    • Tranylcypromine (Parnate®)
    • Selegiline (Zelapar®, Emsam®, and Eldepryl®)
    • Rasagiline (Azilect®)
    • Phenelzine (Nardil®)
    • Isocarboxazid (Marplan®)
  • Salicylates, like:
    • Salsalate (Amigesic®,Disalcid®,and Salflex®)
    • Diflunisal (Dolobid®)
    • Choline magnesium trisalicylate (Trilisate®)
    • Aspirin (Anacin®, Bayer®, and Ecotrin®)
  • Sulfa Drugs (Sulfonamide antibiotics), like:
    • Sulfisoxazole (Gantrisin®)
    • Sulfamethoxazole (Septra®, and Bactrim®)
    • Sulfadoxine (Fansidar®)
    • Sulfadiazine

Interactions Explained

Many of the drugs listed above might contribute t raising the threat of low blood sugar while mixed with Lantus (or any additional insulin medicines). Thus, it would be best to check with your doctor prior to you taking any of these medicines with Lantus. The doctor might advise that you observe your blood sugar levels a bit more closely for a brief period of time in order to check if you have to modify your Lantus dose. Within a few instances, an alternative medicine which doesn’t lead to drug interactions might be advised.

It’s additionally vital that you check with your doctor any time you quit consuming any of the medicines listed within this guide or any time your dosage is adjusted. To repeat, you might have to observe your blood sugar levels a bit more closely for a brief period of time, and your doctor might have to adjust your dosage of Lantus.

Remember that this isn't a exhaustive list of possible drug interactions. So, you ought to speak with your healthcare provider or pharmacist concerning all specific drugs you are taking or plan to be taking.